The L1010 Axiostat dressing is a bioactive hemostatic dressing. It works through a unique mucoadhesion mechanism based on electrical charge, which forms a mechanical barrier over the bleeding area. The production technology is not that of an impregnated dressing, but of a 100% chitosan dressing, free of powder residues or thermal reactions. Chitosan is a natural polysaccharide, composed of glucosamine nanomers and N-acetylglucosamine, resulting in cationically charged chitosan (+Ve). The chitosan has been treated to lower the acidity from pH 6.4 to a physiological pH of 7.4.
It is easy to remove with water; Therefore, it is essential to always protect it from moisture and water with a bandage that is as waterproof as possible, as with all Chitosan products, impregnated or not (100%).
This is a new generation of Indian hemostatic devices, featuring a revolutionary design with protonated bioadhesive PBT technology (Innovation Award 2024 in India). These preparations are unique in that they adhere to tissues when needed and release easily when their function is complete.
The compress version is easy to apply and thanks to its compact and slim packaging, it is convenient to carry. It stops light to severe bleeding and can be torn off, folded, rolled up and also inserted into the wound by hand.
Functions
- 100% chitosan on a folded (non-soaked) compress
- Easy to apply
- Immediately stops moderate to severe bleeding.
- Can be cut, bent and inserted into a deep wound.
- Painless removal by rinsing with a saline solution.
- Certifications: CE 2460/ FDA / MDA / ANVISA and HSA certifications ISO13485/2016
- Country of origin: India
- Shelf life of 5 years. Active on all sides.
- Thin, lightweight and sturdy packaging
- Dimensions: 10 x 10 cm
- Sold individually
Functioning
- The combined effect of bioadhesion and the formation of a strong blood clot provides immediate hemostasis.
- Rapid absorption of blood plasma and inclusion of clotting factors and blood cells in the porous structure by means of electrostatic interaction.
- Maximizing the bio-adhesive property inherent in native chitosan, without any chemical modification of the chitosan spine.
- Creating a solid seal at the site of the combat injury through platelet activation and fibrin formation.
- Hemostasis faster than the natural blood clotting cascade
- Easy to remove from the injury site thanks to neutralization at physiological pH value.
Indications
- Gunshot wounds
- Injuries from stab or knife wounds
- Explosion injuries
- Cuts, scrapes, abrasions
- Arterial and venous bleeding
- Traumatic injuries to the cervical vertebrae and skull
*Note: The essence of PBT® technology lies in optimizing the bioadhesive properties of native chitosan without changing its chemical structure. Structurally, chitosan is a natural polysaccharide, composed of glucosamine and N-acetylglucosamine monomers. Chitosan obtains its positive charge (+ve) by the protonation of the primary amine groups (NH₂) in the glucosamine subunits. However, this protonation is pH-dependent: at a pH above 6.5, chitosan undergoes neutralization and loses its positive charge at a physiological pH of 7.4. Researchers have developed numerous chemical derivatives of chitosan to enhance its positive properties under physiological conditions. However, these chemical modifications often lead to other drawbacks, such as inconsistency, higher processing costs, a risk of toxicity, and a reduction in the molecular weight of chitosan. That’s why we formulated chitosan with (PBT®), using exclusively the physical properties and microscopic morphology of this natural material to maximize the cationic charge.
